About Gastricsin
Gastricsin (PGC) is a protein
from Homo sapiens identified by UniProt accession
P20142, 388 residues long.
MolForge cross-references it against 0 known binders and
190 disease associations.
Target properties
| Protein name | Gastricsin |
|---|
| UniProt accession | P20142 |
|---|
| Gene | PGC |
|---|
| Organism | Homo sapiens |
|---|
| Length | 388 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (190)
Diseases linked to this target (Open Targets).
- mean corpuscular volume · score 0.43
- mean reticulocyte volume · score 0.33
- mean corpuscular hemoglobin concentration · score 0.33
- Red cell distribution width · score 0.26
- BMI-adjusted waist-hip ratio · score 0.18
- sex hormone-binding globulin measurement · score 0.17
- neutrophil count · score 0.16
- waist-hip ratio · score 0.15
- lean body mass · score 0.15
- serum gamma-glutamyl transferase measurement · score 0.14
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P20142-F1 | alphafold | PREDICTED | 88.69 | — |
Amino-acid sequence (388 residues)
MKWMVVVLVC LQLLEAAVVK VPLKKFKSIR ETMKEKGLLG EFLRTHKYDP AWKYRFGDLS VTYEPMAYMD AAYFGEISIG TPPQNFLVLF DTGSSNLWVP SVYCQSQACT SHSRFNPSES STYSTNGQTF SLQYGSGSLT GFFGYDTLTV QSIQVPNQEF GLSENEPGTN FVYAQFDGIM GLAYPALSVD EATTAMQGMV QEGALTSPVF SVYLSNQQGS SGGAVVFGGV DSSLYTGQIY WAPVTQELYW QIGIEEFLIG GQASGWCSEG CQAIVDTGTS LLTVPQQYMS ALLQATGAQE DEYGQFLVNC NSIQNLPSLT FIINGVEFPL PPSSYILSNN GYCTVGVEPT YLSSQNGQPL WILGDVFLRS YYSVYDLGNN RVGFATAA
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