About Kallikrein-2
Kallikrein-2 (KLK2) is a protein
from Homo sapiens identified by UniProt accession
P20151, 261 residues long.
MolForge cross-references it against 0 known binders and
108 disease associations.
Target properties
| Protein name | Kallikrein-2 |
|---|
| UniProt accession | P20151 |
|---|
| Gene | KLK2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 261 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (108)
Diseases linked to this target (Open Targets).
- acute myeloid leukemia · score 0.39
- prostate adenocarcinoma · score 0.38
- prostate carcinoma · score 0.27
- cutaneous melanoma · score 0.27
- lung adenocarcinoma · score 0.24
- cancer biomarker measurement · score 0.24
- breast adenocarcinoma · score 0.22
- non-small cell lung carcinoma · score 0.19
- thyroid carcinoma · score 0.19
- colon adenocarcinoma · score 0.19
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P20151-F1 | alphafold | PREDICTED | 92.40 | — |
Amino-acid sequence (261 residues)
MWDLVLSIAL SVGCTGAVPL IQSRIVGGWE CEKHSQPWQV AVYSHGWAHC GGVLVHPQWV LTAAHCLKKN SQVWLGRHNL FEPEDTGQRV PVSHSFPHPL YNMSLLKHQS LRPDEDSSHD LMLLRLSEPA KITDVVKVLG LPTQEPALGT TCYASGWGSI EPEEFLRPRS LQCVSLHLLS NDMCARAYSE KVTEFMLCAG LWTGGKDTCG GDSGGPLVCN GVLQGITSWG PEPCALPEKP AVYTKVVHYR KWIKDTIAAN P
Explore Kallikrein-2 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets