About Transcription factor BTF3
Transcription factor BTF3 (BTF3) is a protein
from Homo sapiens identified by UniProt accession
P20290, 206 residues long.
MolForge cross-references it against 0 known binders and
116 disease associations.
Target properties
| Protein name | Transcription factor BTF3 |
|---|
| UniProt accession | P20290 |
|---|
| Gene | BTF3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 206 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (116)
Diseases linked to this target (Open Targets).
- Alzheimer disease · score 0.43
- Parkinson disease · score 0.43
- lysosomal storage disease · score 0.43
- neurodegenerative disease · score 0.43
- multiple sclerosis · score 0.43
- body height · score 0.15
- pulse pressure measurement · score 0.13
- heel bone mineral density · score 0.10
- bone quantitative ultrasound measurement · score 0.09
- non-alcoholic fatty liver disease · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P20290-F1 | alphafold | PREDICTED | 72.59 | — |
Amino-acid sequence (206 residues)
MRRTGAPAQA DSRGRGRARG GCPGGEATLS QPPPRGGTRG QEPQMKETIM NQEKLAKLQA QVRIGGKGTA RRKKKVVHRT ATADDKKLQF SLKKLGVNNI SGIEEVNMFT NQGTVIHFNN PKVQASLAAN TFTITGHAET KQLTEMLPSI LNQLGADSLT SLRRLAEALP KQSVDGKAPL ATGEDDDDEV PDLVENFDEA SKNEAN
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