Ras-related protein Rab-4A (RAB4A)

Homo sapiens — UniProt P20338

Gene: RAB4AHomo sapiensSwissProt reviewed

About Ras-related protein Rab-4A

Ras-related protein Rab-4A (RAB4A) is a protein from Homo sapiens identified by UniProt accession P20338, 218 residues long. MolForge cross-references it against 0 known binders and 127 disease associations.

Target properties

Protein nameRas-related protein Rab-4A
UniProt accessionP20338
GeneRAB4A
OrganismHomo sapiens
Length218 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-P20338-F1alphafoldPREDICTED87.51—

Amino-acid sequence (218 residues)

MSQTAMSETY DFLFKFLVIG NAGTGKSCLL HQFIEKKFKD DSNHTIGVEF GSKIINVGGK YVKLQIWDTA GQERFRSVTR SYYRGAAGAL LVYDITSRET YNALTNWLTD ARMLASQNIV IILCGNKKDL DADREVTFLE ASRFAQENEL MFLETSALTG ENVEEAFVQC ARKILNKIES GELDPERMGS GIQYGDAALR QLRSPRRAQA PNAQECGC

Explore Ras-related protein Rab-4A with MolForge

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Quick facts

UniProtP20338
GeneRAB4A
OrganismHomo sapiens
Length218
Binders0
Diseases127
View on UniProt