Ras-related protein Rab-5A (RAB5A)

About Ras-related protein Rab-5A

Ras-related protein Rab-5A (RAB5A) is a protein from Homo sapiens identified by UniProt accession P20339, 215 residues long. MolForge cross-references it against 0 known binders and 182 disease associations.

Target properties

Protein name	Ras-related protein Rab-5A
UniProt accession	P20339
Gene	RAB5A
Organism	Homo sapiens
Length	215 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P20339-F1	alphafold	PREDICTED	84.89	—

Amino-acid sequence (215 residues)

MASRGATRPN GPNTGNKICQ FKLVLLGESA VGKSSLVLRF VKGQFHEFQE STIGAAFLTQ TVCLDDTTVK FEIWDTAGQE RYHSLAPMYY RGAQAAIVVY DITNEESFAR AKNWVKELQR QASPNIVIAL SGNKADLANK RAVDFQEAQS YADDNSLLFM ETSAKTSMNV NEIFMAIAKK LPKNEPQNPG ANSARGRGVD LTEPTQPTRN QCCSN

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards