Pro-MCH (PMCH)

About Pro-MCH

Pro-MCH (PMCH) is a protein from Homo sapiens identified by UniProt accession P20382, 165 residues long. MolForge cross-references it against 0 known binders and 287 disease associations.

Target properties

Protein name	Pro-MCH
UniProt accession	P20382
Gene	PMCH
Organism	Homo sapiens
Length	165 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (287)

Diseases linked to this target (Open Targets).

head and neck squamous cell carcinoma · score 0.16
sitting height measurement · score 0.14
body height · score 0.12
cortical thickness · score 0.09
restless legs syndrome · score 0.08
axial length measurement · score 0.08
Cataplexy · score 0.07
appendicular lean mass · score 0.07
Cholestasis · score 0.06
anxiety · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P20382-F1	alphafold	PREDICTED	56.88	—

Amino-acid sequence (165 residues)

MAKMNLSSYI LILTFSLFSQ GILLSASKSI RNLDDDMVFN TFRLGKGFQK EDTAEKSVIA PSLEQYKNDE SSFMNEEENK VSKNTGSKHN FLNHGLPLNL AIKPYLALKG SVAFPAENGV QNTESTQEKR EIGDEENSAK FPIGRRDFDM LRCMLGRVYR PCWQV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards