Parvalbumin alpha (PVALB)

About Parvalbumin alpha

Parvalbumin alpha (PVALB) is a protein from Homo sapiens identified by UniProt accession P20472, 110 residues long. MolForge cross-references it against 0 known binders and 263 disease associations.

Target properties

Protein name	Parvalbumin alpha
UniProt accession	P20472
Gene	PVALB
Organism	Homo sapiens
Length	110 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (263)

Diseases linked to this target (Open Targets).

bone mineral content measurement · score 0.21
eosinophil count · score 0.10
schizophrenia · score 0.10
basophil count · score 0.10
myeloid sarcoma · score 0.08
Alpers syndrome · score 0.08
sum of eosinophil and basophil counts · score 0.08
Crohn's disease · score 0.08
Obesity · score 0.06
major depressive disorder · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P20472-F1	alphafold	PREDICTED	95.75	—

Amino-acid sequence (110 residues)

MSMTDLLNAE DIKKAVGAFS ATDSFDHKKF FQMVGLKKKS ADDVKKVFHM LDKDKSGFIE EDELGFILKG FSPDARDLSA KETKMLMAAG DKDGDGKIGV DEFSTLVAES

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards