Histone H2A type 1-D (H2AC7)

About Histone H2A type 1-D

Histone H2A type 1-D (H2AC7) is a protein from Homo sapiens identified by UniProt accession P20671, 130 residues long. MolForge cross-references it against 0 known binders and 49 disease associations.

Target properties

Protein name	Histone H2A type 1-D
UniProt accession	P20671
Gene	H2AC7
Organism	Homo sapiens
Length	130 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (49)

Diseases linked to this target (Open Targets).

viral disease · score 0.50
infectious disease · score 0.50
breast carcinoma · score 0.37
cancer · score 0.37
melanoma · score 0.37
BMI-adjusted waist circumference · score 0.10
physical activity measurement · score 0.08
body height · score 0.08
Red cell distribution width · score 0.07
body fat percentage · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P20671-F1	alphafold	PREDICTED	90.94	—

Amino-acid sequence (130 residues)

MSGRGKQGGK ARAKAKTRSS RAGLQFPVGR VHRLLRKGNY SERVGAGAPV YLAAVLEYLT AEILELAGNA ARDNKKTRII PRHLQLAIRN DEELNKLLGK VTIAQGGVLP NIQAVLLPKK TESHHKAKGK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards