About Homeobox protein Hox-A5
Homeobox protein Hox-A5 (HOXA5) is a protein
from Homo sapiens identified by UniProt accession
P20719, 270 residues long.
MolForge cross-references it against 0 known binders and
366 disease associations.
Target properties
| Protein name | Homeobox protein Hox-A5 |
|---|
| UniProt accession | P20719 |
|---|
| Gene | HOXA5 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 270 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (366)
Diseases linked to this target (Open Targets).
- leukocyte count · score 0.21
- vital capacity · score 0.17
- myeloid white cell count · score 0.13
- lymphocyte count · score 0.10
- neoplasm · score 0.10
- non-small cell lung carcinoma · score 0.10
- FEV/FVC ratio · score 0.08
- lung adenocarcinoma · score 0.08
- adrenal cortex carcinoma · score 0.08
- glioblastoma · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P20719-F1 | alphafold | PREDICTED | 61.69 | — |
Amino-acid sequence (270 residues)
MSSYFVNSFC GRYPNGPDYQ LHNYGDHSSV SEQFRDSASM HSGRYGYGYN GMDLSVGRSG SGHFGSGERA RSYAASASAA PAEPRYSQPA TSTHSPQPDP LPCSAVAPSP GSDSHHGGKN SLSNSSGASA DAGSTHISSR EGVGTASGAE EDAPASSEQA SAQSEPSPAP PAQPQIYPWM RKLHISHDNI GGPEGKRART AYTRYQTLEL EKEFHFNRYL TRRRRIEIAH ALCLSERQIK IWFQNRRMKW KKDNKLKSMS MAAAGGAFRP
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