About Mimecan
Mimecan (OGN) is a protein
from Homo sapiens identified by UniProt accession
P20774, 298 residues long.
MolForge cross-references it against 0 known binders and
235 disease associations.
Target properties
| Protein name | Mimecan |
|---|
| UniProt accession | P20774 |
|---|
| Gene | OGN |
|---|
| Organism | Homo sapiens |
|---|
| Length | 298 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (235)
Diseases linked to this target (Open Targets).
- cutaneous melanoma · score 0.26
- lung adenocarcinoma · score 0.26
- urate measurement · score 0.12
- breast adenocarcinoma · score 0.11
- gastric adenocarcinoma · score 0.10
- type 2 diabetes mellitus · score 0.09
- serum alanine aminotransferase measurement · score 0.09
- breast cancer · score 0.08
- neoplasm · score 0.07
- aspartate aminotransferase measurement · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P20774-F1 | alphafold | PREDICTED | 78.82 | — |
Amino-acid sequence (298 residues)
MKTLQSTLLL LLLVPLIKPA PPTQQDSRII YDYGTDNFEE SIFSQDYEDK YLDGKNIKEK ETVIIPNEKS LQLQKDEAIT PLPPKKENDE MPTCLLCVCL SGSVYCEEVD IDAVPPLPKE SAYLYARFNK IKKLTAKDFA DIPNLRRLDF TGNLIEDIED GTFSKLSLLE ELSLAENQLL KLPVLPPKLT LFNAKYNKIK SRGIKANAFK KLNNLTFLYL DHNALESVPL NLPESLRVIH LQFNNIASIT DDTFCKANDT SYIRDRIEEI RLEGNPIVLG KHPNSFICLK RLPIGSYF
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