About Phosducin
Phosducin (PDC) is a protein
from Homo sapiens identified by UniProt accession
P20941, 246 residues long.
MolForge cross-references it against 0 known binders and
340 disease associations.
Target properties
| Protein name | Phosducin |
|---|
| UniProt accession | P20941 |
|---|
| Gene | PDC |
|---|
| Organism | Homo sapiens |
|---|
| Length | 246 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (340)
Diseases linked to this target (Open Targets).
- creatinine measurement · score 0.33
- urate measurement · score 0.27
- cystatin C measurement · score 0.27
- uric acid measurement · score 0.25
- rheumatoid arthritis · score 0.09
- neoplasm · score 0.08
- glomerular filtration rate · score 0.08
- acute myeloid leukemia · score 0.08
- hypertension · score 0.06
- hypertrophic cardiomyopathy · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P20941-F1 | alphafold | PREDICTED | 82.93 | — |
Amino-acid sequence (246 residues)
MEEAKSQSLE EDFEGQATHT GPKGVINDWR KFKLESQDSD SIPPSKKEIL RQMSSPQSRN GKDSKERVSR KMSIQEYELI HKEKEDENCL RKYRRQCMQD MHQKLSFGPR YGFVYELETG KQFLETIEKE LKITTIVVHI YEDGIKGCDA LNSSLTCLAA EYPIVKFCKI KASNTGAGDR FSLDVLPTLL IYKGGELISN FISVAEQFAE EFFAGDVESF LNEYGLLPER EVHVLEHTKI EEEDVE
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