About Myelin and lymphocyte protein
Myelin and lymphocyte protein (MAL) is a protein
from Homo sapiens identified by UniProt accession
P21145, 153 residues long.
MolForge cross-references it against 0 known binders and
91 disease associations.
Target properties
| Protein name | Myelin and lymphocyte protein |
|---|
| UniProt accession | P21145 |
|---|
| Gene | MAL |
|---|
| Organism | Homo sapiens |
|---|
| Length | 153 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (91)
Diseases linked to this target (Open Targets).
- Pelizaeus-Merzbacher-like disease · score 0.37
- neurodegenerative disease · score 0.27
- Nystagmus · score 0.27
- Global developmental delay · score 0.27
- esophageal squamous cell carcinoma · score 0.06
- retinitis pigmentosa · score 0.05
- chronic inflammatory demyelinating polyneuropathy · score 0.05
- clear cell renal carcinoma · score 0.05
- gastric carcinoma · score 0.05
- autosomal dominant slowed nerve conduction velocity · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P21145-F1 | alphafold | PREDICTED | 88.55 | — |
Amino-acid sequence (153 residues)
MAPAAATGGS TLPSGFSVFT TLPDLLFIFE FIFGGLVWIL VASSLVPWPL VQGWVMFVSV FCFVATTTLI ILYIIGAHGG ETSWVTLDAA YHCTAALFYL SASVLEALAT ITMQDGFTYR HYHENIAAVV FSYIATLLYV VHAVFSLIRW KSS
Explore Myelin and lymphocyte protein with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets