About 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT3
3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT3 (FUT3) is a protein
from Homo sapiens identified by UniProt accession
P21217, 361 residues long.
MolForge cross-references it against 0 known binders and
134 disease associations.
Target properties
| Protein name | 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT3 |
|---|
| UniProt accession | P21217 |
|---|
| Gene | FUT3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 361 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (134)
Diseases linked to this target (Open Targets).
- galactoside 34-L-fucosyltransferase measurement · score 0.32
- cholelithiasis · score 0.32
- e-selectin measurement · score 0.31
- blood protein measurement · score 0.29
- Red cell distribution width · score 0.26
- galectin-3 measurement · score 0.25
- cancer antigen 19.9 measurement · score 0.25
- polyp of gallbladder · score 0.21
- metabolite measurement · score 0.12
- cancer biomarker measurement · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P21217-F1 | alphafold | PREDICTED | 89.60 | — |
Amino-acid sequence (361 residues)
MDPLGAAKPQ WPWRRCLAAL LFQLLVAVCF FSYLRVSRDD ATGSPRAPSG SSRQDTTPTR PTLLILLRTW PFHIPVALSR CSEMVPGTAD CHITADRKVY PQADMVIVHH WDIMSNPKSR LPPSPRPQGQ RWIWFNLEPP PNCQHLEALD RYFNLTMSYR SDSDIFTPYG WLEPWSGQPA HPPLNLSAKT ELVAWAVSNW KPDSARVRYY QSLQAHLKVD VYGRSHKPLP KGTMMETLSR YKFYLAFENS LHPDYITEKL WRNALEAWAV PVVLGPSRSN YERFLPPDAF IHVDDFQSPK DLARYLQELD KDHARYLSYF RWRETLRPRS FSWALDFCKA CWKLQQESRY QTVRSIAAWF T
Explore 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT3 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets