About Glutathione S-transferase Mu 3
Glutathione S-transferase Mu 3 (GSTM3) is a protein
from Homo sapiens identified by UniProt accession
P21266, 225 residues long.
MolForge cross-references it against 0 known binders and
164 disease associations.
Target properties
| Protein name | Glutathione S-transferase Mu 3 |
|---|
| UniProt accession | P21266 |
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| Gene | GSTM3 |
|---|
| Organism | Homo sapiens |
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| Length | 225 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (164)
Diseases linked to this target (Open Targets).
- cystic fibrosis · score 0.38
- monocyte count · score 0.16
- high density lipoprotein cholesterol measurement · score 0.12
- protein measurement · score 0.12
- heel bone mineral density · score 0.12
- blood protein measurement · score 0.11
- osteitis deformans · score 0.11
- apolipoprotein A 1 measurement · score 0.10
- Thyroid preparation use measurement · score 0.10
- neoplasm · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P21266-F1 | alphafold | PREDICTED | 96.37 | — |
Amino-acid sequence (225 residues)
MSCESSMVLG YWDIRGLAHA IRLLLEFTDT SYEEKRYTCG EAPDYDRSQW LDVKFKLDLD FPNLPYLLDG KNKITQSNAI LRYIARKHNM CGETEEEKIR VDIIENQVMD FRTQLIRLCY SSDHEKLKPQ YLEELPGQLK QFSMFLGKFS WFAGEKLTFV DFLTYDILDQ NRIFDPKCLD EFPNLKAFMC RFEALEKIAA YLQSDQFCKM PINNKMAQWG NKPVC
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