About Cysteine and glycine-rich protein 1
Cysteine and glycine-rich protein 1 (CSRP1) is a protein
from Homo sapiens identified by UniProt accession
P21291, 193 residues long.
MolForge cross-references it against 0 known binders and
49 disease associations.
Target properties
| Protein name | Cysteine and glycine-rich protein 1 |
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| UniProt accession | P21291 |
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| Gene | CSRP1 |
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| Organism | Homo sapiens |
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| Length | 193 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (49)
Diseases linked to this target (Open Targets).
- acute myeloid leukemia · score 0.09
- heel bone mineral density · score 0.06
- bone density · score 0.06
- bone quantitative ultrasound measurement · score 0.06
- urate measurement · score 0.05
- cortical surface area measurement · score 0.04
- cortical thickness · score 0.04
- brain measurement · score 0.03
- cancer · score 0.03
- atypical teratoid rhabdoid tumor · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P21291-F1 | alphafold | PREDICTED | 71.85 | — |
Amino-acid sequence (193 residues)
MPNWGGGKKC GVCQKTVYFA EEVQCEGNSF HKSCFLCMVC KKNLDSTTVA VHGEEIYCKS CYGKKYGPKG YGYGQGAGTL STDKGESLGI KHEEAPGHRP TTNPNASKFA QKIGGSERCP RCSQAVYAAE KVIGAGKSWH KACFRCAKCG KGLESTTLAD KDGEIYCKGC YAKNFGPKGF GFGQGAGALV HSE
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