About Zinc finger protein 10
Zinc finger protein 10 (ZNF10) is a protein
from Homo sapiens identified by UniProt accession
P21506, 573 residues long.
MolForge cross-references it against 0 known binders and
27 disease associations.
Target properties
| Protein name | Zinc finger protein 10 |
| UniProt accession | P21506 |
| Gene | ZNF10 |
| Organism | Homo sapiens |
| Length | 573 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (27)
Diseases linked to this target (Open Targets).
- type 2 diabetes mellitus · score 0.24
- Abnormality of refraction · score 0.17
- BMI-adjusted waist-hip ratio · score 0.17
- cortical thickness · score 0.12
- mean corpuscular hemoglobin concentration · score 0.11
- cortical surface area measurement · score 0.10
- intraocular pressure measurement · score 0.10
- platelet count · score 0.08
- brain measurement · score 0.06
- cardiovascular disease · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-P21506-F1 | alphafold | PREDICTED | 63.12 | — |
Amino-acid sequence (573 residues)
MDAKSLTAWS RTLVTFKDVF VDFTREEWKL LDTAQQIVYR NVMLENYKNL VSLGYQLTKP DVILRLEKGE EPWLVEREIH QETHPDSETA FEIKSSVSSR SIFKDKQSCD IKMEGMARND LWYLSLEEVW KCRDQLDKYQ ENPERHLRQV AFTQKKVLTQ ERVSESGKYG GNCLLPAQLV LREYFHKRDS HTKSLKHDLV LNGHQDSCAS NSNECGQTFC QNIHLIQFAR THTGDKSYKC PDNDNSLTHG SSLGISKGIH REKPYECKEC GKFFSWRSNL TRHQLIHTGE KPYECKECGK SFSRSSHLIG HQKTHTGEEP YECKECGKSF SWFSHLVTHQ RTHTGDKLYT CNQCGKSFVH SSRLIRHQRT HTGEKPYECP ECGKSFRQST HLILHQRTHV RVRPYECNEC GKSYSQRSHL VVHHRIHTGL KPFECKDCGK CFSRSSHLYS HQRTHTGEKP YECHDCGKSF SQSSALIVHQ RIHTGEKPYE CCQCGKAFIR KNDLIKHQRI HVGEETYKCN QCGIIFSQNS PFIVHQIAHT GEQFLTCNQC GTALVNTSNL IGYQTNHIRE NAY
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