Zinc finger protein 10 (ZNF10)

Homo sapiens — UniProt P21506

Gene: ZNF10Homo sapiensSwissProt reviewed

About Zinc finger protein 10

Zinc finger protein 10 (ZNF10) is a protein from Homo sapiens identified by UniProt accession P21506, 573 residues long. MolForge cross-references it against 0 known binders and 27 disease associations.

Target properties

Protein nameZinc finger protein 10
UniProt accessionP21506
GeneZNF10
OrganismHomo sapiens
Length573 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (27)

Diseases linked to this target (Open Targets).

  • type 2 diabetes mellitus · score 0.24
  • Abnormality of refraction · score 0.17
  • BMI-adjusted waist-hip ratio · score 0.17
  • cortical thickness · score 0.12
  • mean corpuscular hemoglobin concentration · score 0.11
  • cortical surface area measurement · score 0.10
  • intraocular pressure measurement · score 0.10
  • platelet count · score 0.08
  • brain measurement · score 0.06
  • cardiovascular disease · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-P21506-F1alphafoldPREDICTED63.12—

Amino-acid sequence (573 residues)

MDAKSLTAWS RTLVTFKDVF VDFTREEWKL LDTAQQIVYR NVMLENYKNL VSLGYQLTKP DVILRLEKGE EPWLVEREIH QETHPDSETA FEIKSSVSSR SIFKDKQSCD IKMEGMARND LWYLSLEEVW KCRDQLDKYQ ENPERHLRQV AFTQKKVLTQ ERVSESGKYG GNCLLPAQLV LREYFHKRDS HTKSLKHDLV LNGHQDSCAS NSNECGQTFC QNIHLIQFAR THTGDKSYKC PDNDNSLTHG SSLGISKGIH REKPYECKEC GKFFSWRSNL TRHQLIHTGE KPYECKECGK SFSRSSHLIG HQKTHTGEEP YECKECGKSF SWFSHLVTHQ RTHTGDKLYT CNQCGKSFVH SSRLIRHQRT HTGEKPYECP ECGKSFRQST HLILHQRTHV RVRPYECNEC GKSYSQRSHL VVHHRIHTGL KPFECKDCGK CFSRSSHLYS HQRTHTGEKP YECHDCGKSF SQSSALIVHQ RIHTGEKPYE CCQCGKAFIR KNDLIKHQRI HVGEETYKCN QCGIIFSQNS PFIVHQIAHT GEQFLTCNQC GTALVNTSNL IGYQTNHIRE NAY

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Quick facts

UniProtP21506
GeneZNF10
OrganismHomo sapiens
Length573
Binders0
Diseases27
View on UniProt