Diamine acetyltransferase 1 (SAT1)

About Diamine acetyltransferase 1

Diamine acetyltransferase 1 (SAT1) is a protein from Homo sapiens identified by UniProt accession P21673, 171 residues long. MolForge cross-references it against 0 known binders and 123 disease associations.

Target properties

Protein name	Diamine acetyltransferase 1
UniProt accession	P21673
Gene	SAT1
Organism	Homo sapiens
Length	171 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Approved drugs hitting this target (1)

DrugCentral-linked approved drugs that act on this protein.

Disease associations (123)

Diseases linked to this target (Open Targets).

pediatric systemic lupus erythematosus · score 0.37
neurodegenerative disease · score 0.26
colorectal carcinoma · score 0.07
neoplasm · score 0.06
cancer · score 0.05
CIDEC-related familial partial lipodystrophy · score 0.04
glioblastoma · score 0.03
Ataxia · score 0.03
AKT2-related familial partial lipodystrophy · score 0.03
pancreatic neoplasm · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P21673-F1	alphafold	PREDICTED	96.61	—

Amino-acid sequence (171 residues)

MAKFVIRPAT AADCSDILRL IKELAKYEYM EEQVILTEKD LLEDGFGEHP FYHCLVAEVP KEHWTPEGHS IVGFAMYYFT YDPWIGKLLY LEDFFVMSDY RGFGIGSEIL KNLSQVAMRC RCSSMHFLVA EWNEPSINFY KRRGASDLSS EEGWRLFKID KEYLLKMATE E

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards