Fibroblast growth factor 7 (FGF7)

Homo sapiens — UniProt P21781

Gene: FGF7Homo sapiensSwissProt reviewed

About Fibroblast growth factor 7

Fibroblast growth factor 7 (FGF7) is a protein from Homo sapiens identified by UniProt accession P21781, 194 residues long. MolForge cross-references it against 0 known binders and 417 disease associations.

Target properties

Protein nameFibroblast growth factor 7
UniProt accessionP21781
GeneFGF7
OrganismHomo sapiens
Length194 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (417)

Diseases linked to this target (Open Targets).

  • cancer · score 0.60
  • bone development disease · score 0.58
  • female reproductive endometrioid cancer · score 0.50
  • ovarian carcinoma · score 0.46
  • thyroid gland adenocarcinoma · score 0.30
  • glioblastoma multiforme · score 0.30
  • breast adenocarcinoma · score 0.30
  • multiple myeloma · score 0.29
  • endometrial cancer · score 0.29
  • Thyrotoxicosis · score 0.29

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-P21781-F1alphafoldPREDICTED82.44—

Amino-acid sequence (194 residues)

MHKWILTWIL PTLLYRSCFH IICLVGTISL ACNDMTPEQM ATNVNCSSPE RHTRSYDYME GGDIRVRRLF CRTQWYLRID KRGKVKGTQE MKNNYNIMEI RTVAVGIVAI KGVESEFYLA MNKEGKLYAK KECNEDCNFK ELILENHYNT YASAKWTHNG GEMFVALNQK GIPVRGKKTK KEQKTAHFLP MAIT

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Quick facts

UniProtP21781
GeneFGF7
OrganismHomo sapiens
Length194
Binders0
Diseases417
View on UniProt