About Interleukin-10
Interleukin-10 (IL10) is a protein
from Homo sapiens identified by UniProt accession
P22301, 178 residues long.
MolForge cross-references it against 0 known binders and
2,158 disease associations.
Target properties
| Protein name | Interleukin-10 |
|---|
| UniProt accession | P22301 |
|---|
| Gene | IL10 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 178 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (2158)
Diseases linked to this target (Open Targets).
- immune dysregulation-inflammatory bowel disease-arthritis-recurrent infections syndrome · score 0.55
- Crohn's disease · score 0.42
- cancer · score 0.40
- Behcet's syndrome · score 0.29
- inflammatory bowel disease · score 0.26
- ulcerative colitis · score 0.26
- HIV-1 infection · score 0.23
- Oral ulcer · score 0.23
- type 1 diabetes mellitus · score 0.22
- ulcer disease · score 0.21
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P22301-F1 | alphafold | PREDICTED | 87.86 | — |
Amino-acid sequence (178 residues)
MHSSALLCCL VLLTGVRASP GQGTQSENSC THFPGNLPNM LRDLRDAFSR VKTFFQMKDQ LDNLLLKESL LEDFKGYLGC QALSEMIQFY LEEVMPQAEN QDPDIKAHVN SLGENLKTLR LRLRRCHRFL PCENKSKAVE QVKNAFNKLQ EKGIYKAMSE FDIFINYIEA YMTMKIRN
Explore Interleukin-10 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets