About Sterol carrier protein 2
Sterol carrier protein 2 (SCP2) is a protein
from Homo sapiens identified by UniProt accession
P22307, 547 residues long.
MolForge cross-references it against 0 known binders and
159 disease associations.
Target properties
| Protein name | Sterol carrier protein 2 |
|---|
| UniProt accession | P22307 |
|---|
| Gene | SCP2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 547 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (159)
Diseases linked to this target (Open Targets).
- Leukoencephalopathy - dystonia - motor neuropathy · score 0.66
- sterol carrier protein 2 deficiency · score 0.62
- erythrocyte count · score 0.12
- red blood cell density measurement · score 0.12
- leukodystrophy · score 0.12
- sensorineural hearing loss · score 0.12
- Sensorineural hearing impairment · score 0.12
- tuberculin skin test reactivity measurement · score 0.09
- hemoglobin measurement · score 0.09
- monocyte count · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P22307-F1 | alphafold | PREDICTED | 92.28 | — |
Amino-acid sequence (547 residues)
MSSSPWEPAT LRRVFVVGVG MTKFVKPGAE NSRDYPDLAE EAGKKALADA QIPYSAVDQA CVGYVFGDST CGQRAIYHSL GMTGIPIINV NNNCATGSTA LFMARQLIQG GVAECVLALG FEKMSKGSLG IKFSDRTIPT DKHVDLLINK YGLSAHPVAP QMFGYAGKEH MEKYGTKIEH FAKIGWKNHK HSVNNPYSQF QDEYSLDEVM ASKEVFDFLT ILQCCPTSDG AAAAILASEA FVQKYGLQSK AVEILAQEMM TDLPSSFEEK SIIKMVGFDM SKEAARKCYE KSGLTPNDID VIELHDCFST NELLTYEALG LCPEGQGATL VDRGDNTYGG KWVINPSGGL ISKGHPLGAT GLAQCAELCW QLRGEAGKRQ VPGAKVALQH NLGIGGAVVV TLYKMGFPEA ASSFRTHQIE AVPTSSASDG FKANLVFKEI EKKLEEEGEQ FVKKIGGIFA FKVKDGPGGK EATWVVDVKN GKGSVLPNSD KKADCTITMA DSDFLALMTG KMNPQSAFFQ GKLKITGNMG LAMKLQNLQL QPGNAKL
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