About Glutathione peroxidase 3
Glutathione peroxidase 3 (GPX3) is a protein
from Homo sapiens identified by UniProt accession
P22352, 226 residues long.
MolForge cross-references it against 0 known binders and
344 disease associations.
Target properties
| Protein name | Glutathione peroxidase 3 |
|---|
| UniProt accession | P22352 |
|---|
| Gene | GPX3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 226 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (344)
Diseases linked to this target (Open Targets).
- amyotrophic lateral sclerosis · score 0.26
- C-reactive protein measurement · score 0.14
- neoplasm · score 0.11
- MODY · score 0.11
- hepatocellular carcinoma · score 0.10
- type 2 diabetes mellitus · score 0.10
- non-small cell lung carcinoma · score 0.09
- cancer · score 0.09
- axial length measurement · score 0.09
- late-onset Alzheimers disease · score 0.09
Amino-acid sequence (226 residues)
MARLLQASCL LSLLLAGFVS QSRGQEKSKM DCHGGISGTI YEYGALTIDG EEYIPFKQYA GKYVLFVNVA SYUGLTGQYI ELNALQEELA PFGLVILGFP CNQFGKQEPG ENSEILPTLK YVRPGGGFVP NFQLFEKGDV NGEKEQKFYT FLKNSCPPTS ELLGTSDRLF WEPMKVHDIR WNFEKFLVGP DGIPIMRWHH RTTVSNVKMD ILSYMRRQAA LGVKRK
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