About Nucleoside diphosphate kinase B
Nucleoside diphosphate kinase B (NME2) is a protein
from Homo sapiens identified by UniProt accession
P22392, 152 residues long.
MolForge cross-references it against 0 known binders and
139 disease associations.
Target properties
| Protein name | Nucleoside diphosphate kinase B |
|---|
| UniProt accession | P22392 |
|---|
| Gene | NME2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 152 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (139)
Diseases linked to this target (Open Targets).
- body height · score 0.36
- neurodegenerative disease · score 0.36
- sitting height measurement · score 0.28
- white matter microstructure measurement · score 0.24
- BMI-adjusted hip circumference · score 0.18
- body weight · score 0.13
- blood protein measurement · score 0.08
- Arrhythmogenic right ventricular dysplasia · score 0.07
- cancer · score 0.06
- coronary artery disease · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P22392-F1 | alphafold | PREDICTED | 97.66 | — |
Amino-acid sequence (152 residues)
MANLERTFIA IKPDGVQRGL VGEIIKRFEQ KGFRLVAMKF LRASEEHLKQ HYIDLKDRPF FPGLVKYMNS GPVVAMVWEG LNVVKTGRVM LGETNPADSK PGTIRGDFCI QVGRNIIHGS DSVKSAEKEI SLWFKPEELV DYKSCAHDWV YE
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