About Calretinin
Calretinin (CALB2) is a protein
from Homo sapiens identified by UniProt accession
P22676, 271 residues long.
MolForge cross-references it against 0 known binders and
390 disease associations.
Target properties
| Protein name | Calretinin |
|---|
| UniProt accession | P22676 |
|---|
| Gene | CALB2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 271 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (390)
Diseases linked to this target (Open Targets).
- haptoglobin measurement · score 0.27
- hypopituitarism · score 0.26
- body mass index · score 0.26
- pulse pressure measurement · score 0.14
- Miyoshi myopathy · score 0.11
- diastolic blood pressure · score 0.10
- ameloblastoma · score 0.09
- risk-taking behaviour · score 0.09
- mesothelioma · score 0.08
- schizophrenia · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P22676-F1 | alphafold | PREDICTED | 76.82 | — |
Amino-acid sequence (271 residues)
MAGPQQQPPY LHLAELTASQ FLEIWKHFDA DGNGYIEGKE LENFFQELEK ARKGSGMMSK SDNFGEKMKE FMQKYDKNSD GKIEMAELAQ ILPTEENFLL CFRQHVGSSA EFMEAWRKYD TDRSGYIEAN ELKGFLSDLL KKANRPYDEP KLQEYTQTIL RMFDLNGDGK LGLSEMSRLL PVQENFLLKF QGMKLTSEEF NAIFTFYDKD RSGYIDEHEL DALLKDLYEK NKKEMNIQQL TNYRKSVMSL AEAGKLYRKD LEIVLCSEPP M
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