About Carboxypeptidase N subunit 2
Carboxypeptidase N subunit 2 (CPN2) is a protein
from Homo sapiens identified by UniProt accession
P22792, 545 residues long.
MolForge cross-references it against 0 known binders and
25 disease associations.
Target properties
| Protein name | Carboxypeptidase N subunit 2 |
|---|
| UniProt accession | P22792 |
|---|
| Gene | CPN2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 545 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (25)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.48
- body height · score 0.46
- von Willebrand factor measurement · score 0.36
- appendicular lean mass · score 0.33
- interleukin-27 measurement · score 0.31
- TNF-related activation-induced cytokine measurement · score 0.31
- sitting height measurement · score 0.26
- bone density · score 0.24
- urate measurement · score 0.24
- mean platelet volume · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P22792-F1 | alphafold | PREDICTED | 85.59 | — |
Amino-acid sequence (545 residues)
MLPGAWLLWT SLLLLARPAQ PCPMGCDCFV QEVFCSDEEL ATVPLDIPPY TKNIIFVETS FTTLETRAFG SNPNLTKVVF LNTQLCQFRP DAFGGLPRLE DLEVTGSSFL NLSTNIFSNL TSLGKLTLNF NMLEALPEGL FQHLAALESL HLQGNQLQAL PRRLFQPLTH LKTLNLAQNL LAQLPEELFH PLTSLQTLKL SNNALSGLPQ GVFGKLGSLQ ELFLDSNNIS ELPPQVFSQL FCLERLWLQR NAITHLPLSI FASLGNLTFL SLQWNMLRVL PAGLFAHTPC LVGLSLTHNQ LETVAEGTFA HLSNLRSLML SYNAITHLPA GIFRDLEELV KLYLGSNNLT ALHPALFQNL SKLELLSLSK NQLTTLPEGI FDTNYNLFNL ALHGNPWQCD CHLAYLFNWL QQYTDRLLNI QTYCAGPAYL KGQVVPALNE KQLVCPVTRD HLGFQVTWPD ESKAGGSWDL AVQERAARSQ CTYSNPEGTV VLACDQAQCR WLNVQLSPQQ GSLGLQYNAS QEWDLRSSCG SLRLTVSIEA RAAGP
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