About Protein EVI2A
Protein EVI2A (EVI2A) is a protein
from Homo sapiens identified by UniProt accession
P22794, 236 residues long.
MolForge cross-references it against 0 known binders and
100 disease associations.
Target properties
| Protein name | Protein EVI2A |
|---|
| UniProt accession | P22794 |
|---|
| Gene | EVI2A |
|---|
| Organism | Homo sapiens |
|---|
| Length | 236 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (100)
Diseases linked to this target (Open Targets).
- neurofibromatosis type 1 · score 0.34
- sex hormone-binding globulin measurement · score 0.31
- platelet count · score 0.22
- testosterone measurement · score 0.22
- alcohol consumption measurement · score 0.22
- type 2 diabetes mellitus · score 0.22
- lean body mass · score 0.21
- platelet crit · score 0.19
- aspartate aminotransferase measurement · score 0.18
- endometrial carcinoma · score 0.18
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P22794-F1 | alphafold | PREDICTED | 56.71 | — |
Amino-acid sequence (236 residues)
MPTDMEHTGH YLHLAFLMTT VFSLSPGTKA NYTRLWANST SSWDSVIQNK TGRNQNENIN TNPITPEVDY KGNSTNMPET SHIVALTSKS EQELYIPSVV SNSPSTVQSI ENTSKSHGEI FKKDVCAENN NNMAMLICLI IIAVLFLICT FLFLSTVVLA NKVSSLRRSK QVGKRQPRSN GDFLASGLWP AESDTWKRTK QLTGPNLVMQ STGVLTATRE RKDEEGTEKL TNKQIG
Explore Protein EVI2A with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets