Transcription elongation factor A protein 1 (TCEA1)

About Transcription elongation factor A protein 1

Transcription elongation factor A protein 1 (TCEA1) is a protein from Homo sapiens identified by UniProt accession P23193, 301 residues long. MolForge cross-references it against 0 known binders and 122 disease associations.

Target properties

Protein name	Transcription elongation factor A protein 1
UniProt accession	P23193
Gene	TCEA1
Organism	Homo sapiens
Length	301 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (122)

Diseases linked to this target (Open Targets).

HIV infection · score 0.58
salivary gland adenoid cystic carcinoma · score 0.37
Salivary Gland Pleomorphic Adenoma · score 0.37
Parotid Gland Pleomorphic Adenoma · score 0.37
Salivary Gland Carcinoma ex Pleomorphic Adenoma · score 0.37
lipoblastoma · score 0.28
salivary gland mucoepidermoid carcinoma · score 0.28
breast adenocarcinoma · score 0.25
glioblastoma multiforme · score 0.23
gastric adenocarcinoma · score 0.23

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P23193-F1	alphafold	PREDICTED	80.07	—

Amino-acid sequence (301 residues)

MEDEVVRFAK KMDKMVQKKN AAGALDLLKE LKNIPMTLEL LQSTRIGMSV NAIRKQSTDE EVTSLAKSLI KSWKKLLDGP STEKDLDEKK KEPAITSQNS PEAREESTSS GNVSNRKDET NARDTYVSSF PRAPSTSDSV RLKCREMLAA ALRTGDDYIA IGADEEELGS QIEEAIYQEI RNTDMKYKNR VRSRISNLKD AKNPNLRKNV LCGNIPPDLF ARMTAEEMAS DELKEMRKNL TKEAIREHQM AKTGGTQTDL FTCGKCKKKN CTYTQVQTRS ADEPMTTFVV CNECGNRWKF C

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards