Protein S100-A1 (S100A1)

About Protein S100-A1

Protein S100-A1 (S100A1) is a protein from Homo sapiens identified by UniProt accession P23297, 94 residues long. MolForge cross-references it against 0 known binders and 312 disease associations.

Target properties

Protein name	Protein S100-A1
UniProt accession	P23297
Gene	S100A1
Organism	Homo sapiens
Length	94 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (312)

Diseases linked to this target (Open Targets).

inborn error of immunity · score 0.37
neurodegenerative disease · score 0.23
squamous cell lung carcinoma · score 0.16
gastric adenocarcinoma · score 0.13
platelet count · score 0.12
platelet crit · score 0.11
hepatocellular carcinoma · score 0.10
breast cancer · score 0.09
Miyoshi myopathy · score 0.08
head and neck squamous cell carcinoma · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P23297-F1	alphafold	PREDICTED	82.51	—

Amino-acid sequence (94 residues)

MGSELETAME TLINVFHAHS GKEGDKYKLS KKELKELLQT ELSGFLDAQK DVDAVDKVMK ELDENGDGEV DFQEYVVLVA ALTVACNNFF WENS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards