About Myogenic factor 6
Myogenic factor 6 (MYF6) is a protein
from Homo sapiens identified by UniProt accession
P23409, 242 residues long.
MolForge cross-references it against 0 known binders and
163 disease associations.
Target properties
| Protein name | Myogenic factor 6 |
|---|
| UniProt accession | P23409 |
|---|
| Gene | MYF6 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 242 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (163)
Diseases linked to this target (Open Targets).
- endometrial cancer · score 0.23
- autosomal dominant centronuclear myopathy · score 0.19
- centronuclear myopathy · score 0.19
- hepatocellular carcinoma · score 0.13
- type 2 diabetes mellitus · score 0.08
- thoracomelic dysplasia · score 0.07
- Poland syndrome · score 0.07
- cervical rib syndrome · score 0.06
- autosomal recessive spondylocostal dysostosis · score 0.06
- short-rib thoracic dysplasia 17 with or without polydactyly · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P23409-F1 | alphafold | PREDICTED | 66.23 | — |
Amino-acid sequence (242 residues)
MMMDLFETGS YFFYLDGENV TLQPLEVAEG SPLYPGSDGT LSPCQDQMPP EAGSDSSGEE HVLAPPGLQP PHCPGQCLIW ACKTCKRKSA PTDRRKAATL RERRRLKKIN EAFEALKRRT VANPNQRLPK VEILRSAISY IERLQDLLHR LDQQEKMQEL GVDPFSYRPK QENLEGADFL RTCSSQWPSV SDHSRGLVIT AKEGGASIDS SASSSLRCLS SIVDSISSEE RKLPCVEEVV EK
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