About Neurotrophic factor BDNF precursor form
Neurotrophic factor BDNF precursor form (BDNF) is a protein
from Homo sapiens identified by UniProt accession
P23560, 247 residues long.
MolForge cross-references it against 0 known binders and
1,181 disease associations.
Target properties
| Protein name | Neurotrophic factor BDNF precursor form |
|---|
| UniProt accession | P23560 |
|---|
| Gene | BDNF |
|---|
| Organism | Homo sapiens |
|---|
| Length | 247 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (1181)
Diseases linked to this target (Open Targets).
- body mass index · score 0.55
- lean body mass · score 0.54
- body fat percentage · score 0.52
- obesity · score 0.52
- fat body mass · score 0.51
- body weight · score 0.51
- waist circumference · score 0.49
- high density lipoprotein cholesterol measurement · score 0.49
- smoking behavior · score 0.49
- physical activity measurement · score 0.48
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P23560-F1 | alphafold | PREDICTED | 70.99 | — |
Amino-acid sequence (247 residues)
MTILFLTMVI SYFGCMKAAP MKEANIRGQG GLAYPGVRTH GTLESVNGPK AGSRGLTSLA DTFEHVIEEL LDEDQKVRPN EENNKDADLY TSRVMLSSQV PLEPPLLFLL EEYKNYLDAA NMSMRVRRHS DPARRGELSV CDSISEWVTA ADKKTAVDMS GGTVTVLEKV PVSKGQLKQY FYETKCNPMG YTKEGCRGID KRHWNSQCRT TQSYVRALTM DSKKRIGWRF IRIDTSCVCT LTIKRGR
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