About Interleukin-32
Interleukin-32 (IL32) is a protein
from Homo sapiens identified by UniProt accession
P24001, 234 residues long.
MolForge cross-references it against 0 known binders and
359 disease associations.
Target properties
| Protein name | Interleukin-32 |
|---|
| UniProt accession | P24001 |
|---|
| Gene | IL32 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 234 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (359)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.33
- acute myeloid leukemia · score 0.25
- thyroid gland adenocarcinoma · score 0.23
- serum alanine aminotransferase measurement · score 0.23
- aspartate aminotransferase measurement · score 0.19
- neoplasm · score 0.12
- Rheumatoid arthritis · score 0.11
- Miyoshi myopathy · score 0.10
- cancer · score 0.10
- esophageal squamous cell carcinoma · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P24001-F1 | alphafold | PREDICTED | 69.23 | — |
Amino-acid sequence (234 residues)
MCFPKVLSDD MKKLKARMVM LLPTSAQGLG AWVSACDTED TVGHLGPWRD KDPALWCQLC LSSQHQAIER FYDKMQNAES GRGQVMSSLA ELEDDFKEGY LETVAAYYEE QHPELTPLLE KERDGLRCRG NRSPVPDVED PATEEPGESF CDKVMRWFQA MLQRLQTWWH GVLAWVKEKV VALVHAVQAL WKQFQSFCCS LSELFMSSFQ SYGAPRGDKE ELTPQKCSEP QSSK
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