Cytochrome c oxidase subunit 7A1, mitochondrial…

About Cytochrome c oxidase subunit 7A1, mitochondrial

Cytochrome c oxidase subunit 7A1, mitochondrial (COX7A1) is a protein from Homo sapiens identified by UniProt accession P24310, 79 residues long. MolForge cross-references it against 0 known binders and 125 disease associations.

Target properties

Protein name	Cytochrome c oxidase subunit 7A1, mitochondrial
UniProt accession	P24310
Gene	COX7A1
Organism	Homo sapiens
Length	79 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (125)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.55
Alzheimer disease · score 0.34
lysosomal storage disease · score 0.33
multiple sclerosis · score 0.33
Parkinson disease · score 0.33
neuroinflammatory disorder · score 0.31
non-small cell lung carcinoma · score 0.08
cancer · score 0.07
lung cancer · score 0.07
hypertrophic cardiomyopathy · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P24310-F1	alphafold	PREDICTED	88.38	—

Amino-acid sequence (79 residues)

MQALRVSQAL IRSFSSTARN RFQNRVREKQ KLFQEDNDIP LYLKGGIVDN ILYRVTMTLC LGGTVYSLYS LGWASFPRN

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Cytochrome c oxidase subunit 7A1, mitochondrial (COX7A1)