Cytochrome c oxidase subunit 7B, mitochondrial (COX7B)

About Cytochrome c oxidase subunit 7B, mitochondrial

Cytochrome c oxidase subunit 7B, mitochondrial (COX7B) is a protein from Homo sapiens identified by UniProt accession P24311, 80 residues long. MolForge cross-references it against 0 known binders and 78 disease associations.

Target properties

Protein name	Cytochrome c oxidase subunit 7B, mitochondrial
UniProt accession	P24311
Gene	COX7B
Organism	Homo sapiens
Length	80 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (78)

Diseases linked to this target (Open Targets).

Microphthalmia with linear skin defects syndrome · score 0.76
neurodegenerative disease · score 0.56
linear skin defects with multiple congenital anomalies · score 0.50
lysosomal storage disease · score 0.40
Parkinson disease · score 0.36
multiple sclerosis · score 0.36
Alzheimer disease · score 0.36
neuroinflammatory disorder · score 0.25
endometrial cancer · score 0.18
Graves disease · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P24311-F1	alphafold	PREDICTED	90.58	—

Amino-acid sequence (80 residues)

MFPLVKSALN RLQVRSIQQT MARQSHQKRT PDFHDKYGNA VLASGATFCI VTWTYVATQV GIEWNLSPVG RVTPKEWRNQ

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards