About Elongation factor 1-beta
Elongation factor 1-beta (EEF1B2) is a protein
from Homo sapiens identified by UniProt accession
P24534, 225 residues long.
MolForge cross-references it against 0 known binders and
83 disease associations.
Target properties
| Protein name | Elongation factor 1-beta |
|---|
| UniProt accession | P24534 |
|---|
| Gene | EEF1B2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 225 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (83)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.47
- Global developmental delay · score 0.43
- autosomal recessive non-syndromic intellectual disability · score 0.42
- Intellectual disability · score 0.34
- Seizure · score 0.34
- Moderate global developmental delay · score 0.34
- genetic disorder · score 0.18
- self reported educational attainment · score 0.18
- BMI-adjusted waist-hip ratio · score 0.16
- CCL28 measurement · score 0.15
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P24534-F1 | alphafold | PREDICTED | 77.29 | — |
Amino-acid sequence (225 residues)
MGFGDLKSPA GLQVLNDYLA DKSYIEGYVP SQADVAVFEA VSSPPPADLC HALRWYNHIK SYEKEKASLP GVKKALGKYG PADVEDTTGS GATDSKDDDD IDLFGSDDEE ESEEAKRLRE ERLAQYESKK AKKPALVAKS SILLDVKPWD DETDMAKLEE CVRSIQADGL VWGSSKLVPV GYGIKKLQIQ CVVEDDKVGT DMLEEQITAF EDYVQSMDVA AFNKI
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