About Myosin regulatory light polypeptide 9
Myosin regulatory light polypeptide 9 (MYL9) is a protein
from Homo sapiens identified by UniProt accession
P24844, 172 residues long.
MolForge cross-references it against 0 known binders and
165 disease associations.
Target properties
| Protein name | Myosin regulatory light polypeptide 9 |
|---|
| UniProt accession | P24844 |
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| Gene | MYL9 |
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| Organism | Homo sapiens |
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| Length | 172 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (165)
Diseases linked to this target (Open Targets).
- megacystis-microcolon-intestinal hypoperistalsis syndrome 4 · score 0.55
- familial visceral myopathy · score 0.30
- visceral myopathy 1 · score 0.29
- head and neck squamous cell carcinoma · score 0.19
- lung adenocarcinoma · score 0.19
- cutaneous melanoma · score 0.13
- diastolic blood pressure · score 0.12
- neoplasm · score 0.10
- endometrial cancer · score 0.09
- cancer · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P24844-F1 | alphafold | PREDICTED | 83.78 | — |
Amino-acid sequence (172 residues)
MSSKRAKAKT TKKRPQRATS NVFAMFDQSQ IQEFKEAFNM IDQNRDGFID KEDLHDMLAS LGKNPTDEYL EGMMSEAPGP INFTMFLTMF GEKLNGTDPE DVIRNAFACF DEEASGFIHE DHLRELLTTM GDRFTDEEVD EMYREAPIDK KGNFNYVEFT RILKHGAKDK DD
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