About Cyclin-C
Cyclin-C (CCNC) is a protein
from Homo sapiens identified by UniProt accession
P24863, 283 residues long.
MolForge cross-references it against 0 known binders and
126 disease associations.
Target properties
| Protein name | Cyclin-C |
|---|
| UniProt accession | P24863 |
|---|
| Gene | CCNC |
|---|
| Organism | Homo sapiens |
|---|
| Length | 283 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (126)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.55
- cancer · score 0.38
- breast adenocarcinoma · score 0.24
- rhabdomyosarcoma · score 0.20
- hepatocellular carcinoma · score 0.19
- colon adenocarcinoma · score 0.19
- breast carcinoma · score 0.19
- rectal adenocarcinoma · score 0.19
- gastric adenocarcinoma · score 0.19
- prostate adenocarcinoma · score 0.19
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P24863-F1 | alphafold | PREDICTED | 91.42 | — |
Amino-acid sequence (283 residues)
MAGNFWQSSH YLQWILDKQD LLKERQKDLK FLSEEEYWKL QIFFTNVIQA LGEHLKLRQQ VIATATVYFK RFYARYSLKS IDPVLMAPTC VFLASKVEEF GVVSNTRLIA AATSVLKTRF SYAFPKEFPY RMNHILECEF YLLELMDCCL IVYHPYRPLL QYVQDMGQED MLLPLAWRIV NDTYRTDLCL LYPPFMIALA CLHVACVVQQ KDARQWFAEL SVDMEKILEI IRVILKLYEQ WKNFDERKEM ATILSKMPKP KPPPNSEGEQ GPNGSQNSSY SQS
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