About Zinc-alpha-2-glycoprotein
Zinc-alpha-2-glycoprotein (AZGP1) is a protein
from Homo sapiens identified by UniProt accession
P25311, 298 residues long.
MolForge cross-references it against 0 known binders and
241 disease associations.
Target properties
| Protein name | Zinc-alpha-2-glycoprotein |
|---|
| UniProt accession | P25311 |
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| Gene | AZGP1 |
|---|
| Organism | Homo sapiens |
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| Length | 298 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
|---|
Disease associations (241)
Diseases linked to this target (Open Targets).
- body weight · score 0.21
- mathematical ability · score 0.20
- blood protein measurement · score 0.16
- interstitial lung disease · score 0.12
- neoplasm · score 0.11
- HbA1c measurement · score 0.11
- Abnormality of refraction · score 0.10
- triple-negative breast cancer · score 0.09
- hepatocellular carcinoma · score 0.09
- cancer · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P25311-F1 | alphafold | PREDICTED | 92.87 | — |
Amino-acid sequence (298 residues)
MVRMVPVLLS LLLLLGPAVP QENQDGRYSL TYIYTGLSKH VEDVPAFQAL GSLNDLQFFR YNSKDRKSQP MGLWRQVEGM EDWKQDSQLQ KAREDIFMET LKDIVEYYND SNGSHVLQGR FGCEIENNRS SGAFWKYYYD GKDYIEFNKE IPAWVPFDPA AQITKQKWEA EPVYVQRAKA YLEEECPATL RKYLKYSKNI LDRQDPPSVV VTSHQAPGEK KKLKCLAYDF YPGKIDVHWT RAGEVQEPEL RGDVLHNGNG TYQSWVVVAV PPQDTAPYSC HVQHSSLAQP LVVPWEAS
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