Metallothionein-3 (MT3)

About Metallothionein-3

Metallothionein-3 (MT3) is a protein from Homo sapiens identified by UniProt accession P25713, 68 residues long. MolForge cross-references it against 0 known binders and 154 disease associations.

Target properties

Protein name	Metallothionein-3
UniProt accession	P25713
Gene	MT3
Organism	Homo sapiens
Length	68 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (154)

Diseases linked to this target (Open Targets).

urinary bladder carcinoma · score 0.09
neoplasm · score 0.09
acute myeloid leukemia · score 0.08
melanoma · score 0.08
esophageal squamous cell carcinoma · score 0.07
Pallister-Hall syndrome · score 0.07
squamous cell carcinoma · score 0.05
hepatocellular carcinoma · score 0.04
non-small cell lung carcinoma · score 0.04
benign prostatic hyperplasia · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P25713-F1	alphafold	PREDICTED	69.11	—

Amino-acid sequence (68 residues)

MDPETCPCPS GGSCTCADSC KCEGCKCTSC KKSCCSCCPA ECEKCAKDCV CKGGEAAEAE AEKCSCCQ

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards