About Rhombotin-2
Rhombotin-2 (LMO2) is a protein
from Homo sapiens identified by UniProt accession
P25791, 158 residues long.
MolForge cross-references it against 0 known binders and
302 disease associations.
Target properties
| Protein name | Rhombotin-2 |
|---|
| UniProt accession | P25791 |
|---|
| Gene | LMO2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 158 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (302)
Diseases linked to this target (Open Targets).
- eosinophil count · score 0.47
- mean corpuscular volume · score 0.47
- neurodegenerative disease · score 0.46
- erythrocyte count · score 0.45
- monocyte count · score 0.44
- mean corpuscular hemoglobin · score 0.43
- mean corpuscular hemoglobin concentration · score 0.41
- eosinophil percentage of leukocytes · score 0.39
- basophil count · score 0.39
- mean reticulocyte volume · score 0.38
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P25791-F1 | alphafold | PREDICTED | 90.44 | — |
Amino-acid sequence (158 residues)
MSSAIERKSL DPSEEPVDEV LQIPPSLLTC GGCQQNIGDR YFLKAIDQYW HEDCLSCDLC GCRLGEVGRR LYYKLGRKLC RRDYLRLFGQ DGLCASCDKR IRAYEMTMRV KDKVYHLECF KCAACQKHFC VGDRYLLINS DIVCEQDIYE WTKINGMI
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