About Rhombotin-1
Rhombotin-1 (LMO1) is a protein
from Homo sapiens identified by UniProt accession
P25800, 156 residues long.
MolForge cross-references it against 0 known binders and
161 disease associations.
Target properties
| Protein name | Rhombotin-1 |
|---|
| UniProt accession | P25800 |
|---|
| Gene | LMO1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 156 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (161)
Diseases linked to this target (Open Targets).
- neuroblastoma · score 0.45
- body height · score 0.44
- glucose measurement · score 0.42
- birth weight · score 0.39
- serum albumin measurement · score 0.38
- gastric carcinoma · score 0.37
- esophageal adenocarcinoma · score 0.37
- Hepatobiliary Neoplasm · score 0.37
- colorectal adenocarcinoma · score 0.37
- Ovarian Endometrioid Adenocarcinoma with Squamous Differentiation · score 0.37
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P25800-F1 | alphafold | PREDICTED | 88.18 | — |
Amino-acid sequence (156 residues)
MMVLDKEDGV PMLSVQPKGK QKGCAGCNRK IKDRYLLKAL DKYWHEDCLK CACCDCRLGE VGSTLYTKAN LILCRRDYLR LFGTTGNCAA CSKLIPAFEM VMRARDNVYH LDCFACQLCN QRFCVGDKFF LKNNMILCQM DYEEGQLNGT FESQVQ
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