Tumor necrosis factor receptor superfamily member 5 (CD40)

Homo sapiens — UniProt P25942

Gene: CD40Homo sapiensSwissProt reviewed

About Tumor necrosis factor receptor superfamily member 5

Tumor necrosis factor receptor superfamily member 5 (CD40) is a protein from Homo sapiens identified by UniProt accession P25942, 277 residues long. MolForge cross-references it against 0 known binders and 976 disease associations.

Target properties

Protein nameTumor necrosis factor receptor superfamily member 5
UniProt accessionP25942
GeneCD40
OrganismHomo sapiens
Length277 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-P25942-F1alphafoldPREDICTED81.19—

Amino-acid sequence (277 residues)

MVRLPLQCVL WGCLLTAVHP EPPTACREKQ YLINSQCCSL CQPGQKLVSD CTEFTETECL PCGESEFLDT WNRETHCHQH KYCDPNLGLR VQQKGTSETD TICTCEEGWH CTSEACESCV LHRSCSPGFG VKQIATGVSD TICEPCPVGF FSNVSSAFEK CHPWTSCETK DLVVQQAGTN KTDVVCGPQD RLRALVVIPI IFGILFAILL VLVFIKKVAK KPTNKAPHPK QEPQEINFPD DLPGSNTAAP VQETLHGCQP VTQEDGKESR ISVQERQ

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Explore Tumor necrosis factor receptor superfamily member 5 with MolForge

Find binders, run structure-based screening, and map this target across diseases and approved drugs with our AI-powered platform.

Browse all targets

Quick facts

UniProtP25942
GeneCD40
OrganismHomo sapiens
Length277
Binders0
Diseases976
View on UniProt