Keratin-associated protein 5-9 (KRTAP5-9)

About Keratin-associated protein 5-9

Keratin-associated protein 5-9 (KRTAP5-9) is a protein from Homo sapiens identified by UniProt accession P26371, 169 residues long. MolForge cross-references it against 0 known binders and 10 disease associations.

Target properties

Protein name	Keratin-associated protein 5-9
UniProt accession	P26371
Gene	KRTAP5-9
Organism	Homo sapiens
Length	169 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (10)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.33
head and neck squamous cell carcinoma · score 0.18
esophageal cancer · score 0.14
neuroblastoma · score 0.13
protein measurement · score 0.10
vitamin D measurement · score 0.06
pancreatic adenocarcinoma · score 0.04
Hodgkins lymphoma · score 0.03
adolescent idiopathic scoliosis · score 0.03
diabetes mellitus · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P26371-F1	alphafold	PREDICTED	40.94	—

Amino-acid sequence (169 residues)

MGCCGCSGGC GSSCGGCDSS CGSCGSGCRG CGPSCCAPVY CCKPVCCCVP ACSCSSCGKR GCGSCGGSKG GCGSCGCSQC SCCKPCCCSS GCGSSCCQCS CCKPYCSQCS CCKPCCSSSG RGSSCCQSSC CKPCCSSSGC GSSCCQSSCC KPCCSQSRCC VPVCYQCKI

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards