ELAV-like protein 4 (ELAVL4)

About ELAV-like protein 4

ELAV-like protein 4 (ELAVL4) is a protein from Homo sapiens identified by UniProt accession P26378, 385 residues long. MolForge cross-references it against 0 known binders and 125 disease associations.

Target properties

Protein name	ELAV-like protein 4
UniProt accession	P26378
Gene	ELAVL4
Organism	Homo sapiens
Length	385 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (125)

Diseases linked to this target (Open Targets).

body mass index · score 0.40
smoking status measurement · score 0.37
neurodegenerative disease · score 0.37
attention deficit hyperactivity disorder · score 0.33
antisocial behaviour measurement · score 0.32
substance abuse · score 0.32
smoking behavior · score 0.31
smoking initiation · score 0.30
smoking cessation · score 0.30
lean body mass · score 0.29

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P26378-F1	alphafold	PREDICTED	73.80	—

Amino-acid sequence (385 residues)

MEWNGLKMII STMEPQVSNG PTSNTSNGPS SNNRNCPSPM QTGATTDDSK TNLIVNYLPQ NMTQEEFRSL FGSIGEIESC KLVRDKITGQ SLGYGFVNYI DPKDAEKAIN TLNGLRLQTK TIKVSYARPS SASIRDANLY VSGLPKTMTQ KELEQLFSQY GRIITSRILV DQVTGVSRGV GFIRFDKRIE AEEAIKGLNG QKPSGATEPI TVKFANNPSQ KSSQALLSQL YQSPNRRYPG PLHHQAQRFR LDNLLNMAYG VKRLMSGPVP PSACPPRFSP ITIDGMTSLV GMNIPGHTGT GWCIFVYNLS PDSDESVLWQ LFGPFGAVNN VKVIRDFNTN KCKGFGFVTM TNYDEAAMAI ASLNGYRLGD RVLQVSFKTN KAHKS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards