About Acrosomal protein SP-10
Acrosomal protein SP-10 (ACRV1) is a protein
from Homo sapiens identified by UniProt accession
P26436, 265 residues long.
MolForge cross-references it against 0 known binders and
36 disease associations.
Target properties
| Protein name | Acrosomal protein SP-10 |
|---|
| UniProt accession | P26436 |
|---|
| Gene | ACRV1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 265 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (36)
Diseases linked to this target (Open Targets).
- platelet count · score 0.24
- Red cell distribution width · score 0.13
- prostate carcinoma · score 0.12
- prostate cancer · score 0.11
- Familial prostate cancer · score 0.11
- heel bone mineral density · score 0.04
- vital capacity · score 0.04
- mean platelet volume · score 0.04
- mean corpuscular volume · score 0.04
- cancer · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P26436-F1 | alphafold | PREDICTED | 61.73 | — |
Amino-acid sequence (265 residues)
MNRFLLLMSL YLLGSARGTS SQPNELSGSI DHQTSVQQLP GEFFSLENPS DAEALYETSS GLNTLSEHGS SEHGSSKHTV AEHTSGEHAE SEHASGEPAA TEHAEGEHTV GEQPSGEQPS GEHLSGEQPL SELESGEQPS DEQPSGEHGS GEQPSGEQAS GEQPSGEHAS GEQASGAPIS STSTGTILNC YTCAYMNDQG KCLRGEGTCI TQNSQQCMLK KIFEGGKLQF MVQGCENMCP SMNLFSHGTR MQIICCRNQS FCNKI
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