mRNA decay activator protein ZFP36 (ZFP36)

About mRNA decay activator protein ZFP36

mRNA decay activator protein ZFP36 (ZFP36) is a protein from Homo sapiens identified by UniProt accession P26651, 326 residues long. MolForge cross-references it against 0 known binders and 318 disease associations.

Target properties

Protein name	mRNA decay activator protein ZFP36
UniProt accession	P26651
Gene	ZFP36
Organism	Homo sapiens
Length	326 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P26651-F1	alphafold	PREDICTED	62.06	—

Amino-acid sequence (326 residues)

MDLTAIYESL LSLSPDVPVP SDHGGTESSP GWGSSGPWSL SPSDSSPSGV TSRLPGRSTS LVEGRSCGWV PPPPGFAPLA PRLGPELSPS PTSPTATSTT PSRYKTELCR TFSESGRCRY GAKCQFAHGL GELRQANRHP KYKTELCHKF YLQGRCPYGS RCHFIHNPSE DLAAPGHPPV LRQSISFSGL PSGRRTSPPP PGLAGPSLSS SSFSPSSSPP PPGDLPLSPS AFSAAPGTPL ARRDPTPVCC PSCRRATPIS VWGPLGGLVR TPSVQSLGSD PDEYASSGSS LGGSDSPVFE AGVFAPPQPV AAPRRLPIFN RISVSE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards