About CD27 antigen
CD27 antigen (CD27) is a protein
from Homo sapiens identified by UniProt accession
P26842, 260 residues long.
MolForge cross-references it against 0 known binders and
572 disease associations.
Target properties
| Protein name | CD27 antigen |
|---|
| UniProt accession | P26842 |
|---|
| Gene | CD27 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 260 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (572)
Diseases linked to this target (Open Targets).
- lymphoproliferative syndrome · score 0.66
- combined immunodeficiency · score 0.57
- autosomal recessive lymphoproliferative disease · score 0.55
- Combined immunodeficiency · score 0.46
- Immunodeficiency · score 0.43
- Combined T and B cell immunodeficiency · score 0.43
- neurodegenerative disease · score 0.38
- blood protein measurement · score 0.34
- cortical surface area measurement · score 0.20
- genetic disorder · score 0.19
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P26842-F1 | alphafold | PREDICTED | 71.69 | — |
Amino-acid sequence (260 residues)
MARPHPWWLC VLGTLVGLSA TPAPKSCPER HYWAQGKLCC QMCEPGTFLV KDCDQHRKAA QCDPCIPGVS FSPDHHTRPH CESCRHCNSG LLVRNCTITA NAECACRNGW QCRDKECTEC DPLPNPSLTA RSSQALSPHP QPTHLPYVSE MLEARTAGHM QTLADFRQLP ARTLSTHWPP QRSLCSSDFI RILVIFSGMF LVFTLAGALF LHQRRKYRSN KGESPVEPAE PCHYSCPREE EGSTIPIQED YRKPEPACSP
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