Peptidyl-prolyl cis-trans isomerase FKBP2 (FKBP2)

About Peptidyl-prolyl cis-trans isomerase FKBP2

Peptidyl-prolyl cis-trans isomerase FKBP2 (FKBP2) is a protein from Homo sapiens identified by UniProt accession P26885, 142 residues long. MolForge cross-references it against 0 known binders and 62 disease associations.

Target properties

Protein name	Peptidyl-prolyl cis-trans isomerase FKBP2
UniProt accession	P26885
Gene	FKBP2
Organism	Homo sapiens
Length	142 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (62)

Diseases linked to this target (Open Targets).

cognitive function measurement · score 0.21
bipolar disorder · score 0.21
diet measurement · score 0.12
mean corpuscular volume · score 0.09
body mass index · score 0.08
platelet count · score 0.06
lean body mass · score 0.06
eosinophil percentage of leukocytes · score 0.06
intelligence · score 0.05
eosinophil count · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P26885-F1	alphafold	PREDICTED	89.50	—

Amino-acid sequence (142 residues)

MRLSWFRVLT VLSICLSAVA TATGAEGKRK LQIGVKKRVD HCPIKSRKGD VLHMHYTGKL EDGTEFDSSL PQNQPFVFSL GTGQVIKGWD QGLLGMCEGE KRKLVIPSEL GYGERGAPPK IPGGATLVFE VELLKIERRT EL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards