Annexin A13 (ANXA13)

Homo sapiens — UniProt P27216

Gene: ANXA13Homo sapiensSwissProt reviewed

About Annexin A13

Annexin A13 (ANXA13) is a protein from Homo sapiens identified by UniProt accession P27216, 316 residues long. MolForge cross-references it against 0 known binders and 62 disease associations.

Target properties

Protein nameAnnexin A13
UniProt accessionP27216
GeneANXA13
OrganismHomo sapiens
Length316 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (62)

Diseases linked to this target (Open Targets).

  • breast carcinoma · score 0.37
  • Otitis media · score 0.29
  • eustachian tube disease · score 0.29
  • estrogen-receptor negative breast cancer · score 0.26
  • Barrett's esophagus · score 0.08
  • nonpapillary renal cell carcinoma · score 0.07
  • neoplasm · score 0.07
  • carotid artery intima media thickness · score 0.07
  • major depressive disorder · score 0.07
  • obsessive-compulsive disorder · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-P27216-F1alphafoldPREDICTED94.78—

Amino-acid sequence (316 residues)

MGNRHAKASS PQGFDVDRDA KKLNKACKGM GTNEAAIIEI LSGRTSDERQ QIKQKYKATY GKELEEVLKS ELSGNFEKTA LALLDRPSEY AARQLQKAMK GLGTDESVLI EVLCTRTNKE IIAIKEAYQR LFDRSLESDV KGDTSGNLKK ILVSLLQANR NEGDDVDKDL AGQDAKDLYD AGEGRWGTDE LAFNEVLAKR SYKQLRATFQ AYQILIGKDI EEAIEEETSG DLQKAYLTLV RCAQDCEDYF AERLYKSMKG AGTDEETLIR IVVTRAEVDL QGIKAKFQEK YQKSLSDMVR SDTSGDFRKL LVALLH

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Quick facts

UniProtP27216
GeneANXA13
OrganismHomo sapiens
Length316
Binders0
Diseases62
View on UniProt