About Annexin A13
Annexin A13 (ANXA13) is a protein
from Homo sapiens identified by UniProt accession
P27216, 316 residues long.
MolForge cross-references it against 0 known binders and
62 disease associations.
Target properties
| Protein name | Annexin A13 |
| UniProt accession | P27216 |
| Gene | ANXA13 |
| Organism | Homo sapiens |
| Length | 316 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (62)
Diseases linked to this target (Open Targets).
- breast carcinoma · score 0.37
- Otitis media · score 0.29
- eustachian tube disease · score 0.29
- estrogen-receptor negative breast cancer · score 0.26
- Barrett's esophagus · score 0.08
- nonpapillary renal cell carcinoma · score 0.07
- neoplasm · score 0.07
- carotid artery intima media thickness · score 0.07
- major depressive disorder · score 0.07
- obsessive-compulsive disorder · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-P27216-F1 | alphafold | PREDICTED | 94.78 | — |
Amino-acid sequence (316 residues)
MGNRHAKASS PQGFDVDRDA KKLNKACKGM GTNEAAIIEI LSGRTSDERQ QIKQKYKATY GKELEEVLKS ELSGNFEKTA LALLDRPSEY AARQLQKAMK GLGTDESVLI EVLCTRTNKE IIAIKEAYQR LFDRSLESDV KGDTSGNLKK ILVSLLQANR NEGDDVDKDL AGQDAKDLYD AGEGRWGTDE LAFNEVLAKR SYKQLRATFQ AYQILIGKDI EEAIEEETSG DLQKAYLTLV RCAQDCEDYF AERLYKSMKG AGTDEETLIR IVVTRAEVDL QGIKAKFQEK YQKSLSDMVR SDTSGDFRKL LVALLH
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