G0/G1 switch protein 2 (G0S2)

About G0/G1 switch protein 2

G0/G1 switch protein 2 (G0S2) is a protein from Homo sapiens identified by UniProt accession P27469, 103 residues long. MolForge cross-references it against 0 known binders and 166 disease associations.

Target properties

Protein name	G0/G1 switch protein 2
UniProt accession	P27469
Gene	G0S2
Organism	Homo sapiens
Length	103 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (166)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.26
aspartate aminotransferase measurement · score 0.23
body mass index · score 0.11
protein measurement · score 0.10
waist circumference · score 0.08
hip circumference · score 0.08
chronic myelogenous leukemia · score 0.08
acute myocardial infarction · score 0.06
cleft palate · score 0.06
squamous cell carcinoma · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P27469-F1	alphafold	PREDICTED	76.81	—

Amino-acid sequence (103 residues)

METVQELIPL AKEMMAQKRK GKMVKLYVLG SVLALFGVVL GLMETVCSPF TAARRLRDQE AAVAELQAAL ERQALQKQAL QEKGKQQDTV LGGRALSNRQ HAS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards