Calmodulin-like protein 3 (CALML3)

About Calmodulin-like protein 3

Calmodulin-like protein 3 (CALML3) is a protein from Homo sapiens identified by UniProt accession P27482, 149 residues long. MolForge cross-references it against 0 known binders and 61 disease associations.

Target properties

Protein name	Calmodulin-like protein 3
UniProt accession	P27482
Gene	CALML3
Organism	Homo sapiens
Length	149 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Approved drugs hitting this target (1)

DrugCentral-linked approved drugs that act on this protein.

Disease associations (61)

Diseases linked to this target (Open Targets).

cortical surface area measurement · score 0.26
heel bone mineral density · score 0.22
brain measurement · score 0.22
FEV/FVC ratio · score 0.11
waist-hip ratio · score 0.10
BMI-adjusted waist-hip ratio · score 0.09
PHF-tau measurement · score 0.09
neoplasm · score 0.08
hepatocellular carcinoma · score 0.08
papillary thyroid carcinoma · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P27482-F1	alphafold	PREDICTED	83.22	—

Amino-acid sequence (149 residues)

MADQLTEEQV TEFKEAFSLF DKDGDGCITT RELGTVMRSL GQNPTEAELR DMMSEIDRDG NGTVDFPEFL GMMARKMKDT DNEEEIREAF RVFDKDGNGF VSAAELRHVM TRLGEKLSDE EVDEMIRAAD TDGDGQVNYE EFVRVLVSK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards