About Large ribosomal subunit protein uL16
Large ribosomal subunit protein uL16 (RPL10) is a protein
from Homo sapiens identified by UniProt accession
P27635, 214 residues long.
MolForge cross-references it against 0 known binders and
118 disease associations.
Target properties
| Protein name | Large ribosomal subunit protein uL16 |
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| UniProt accession | P27635 |
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| Gene | RPL10 |
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| Organism | Homo sapiens |
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| Length | 214 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (118)
Diseases linked to this target (Open Targets).
- intellectual disability, X-linked, syndromic, 35 · score 0.71
- X-linked intellectual disability - psychosis - macroorchidism · score 0.56
- Duchenne muscular dystrophy · score 0.50
- cystic fibrosis · score 0.50
- influenza · score 0.46
- multiple myeloma · score 0.44
- autism · score 0.43
- T-cell acute lymphoblastic leukemia · score 0.37
- cutaneous melanoma · score 0.37
- Hepatobiliary Neoplasm · score 0.37
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P27635-F1 | alphafold | PREDICTED | 94.60 | — |
Amino-acid sequence (214 residues)
MGRRPARCYR YCKNKPYPKS RFCRGVPDAK IRIFDLGRKK AKVDEFPLCG HMVSDEYEQL SSEALEAARI CANKYMVKSC GKDGFHIRVR LHPFHVIRIN KMLSCAGADR LQTGMRGAFG KPQGTVARVH IGQVIMSIRT KLQNKEHVIE ALRRAKFKFP GRQKIHISKK WGFTKFNADE FEDMVAEKRL IPDGCGVKYI PSRGPLDKWR ALHS
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